马来酸桂派齐特注射液治疗缺血性脑损伤的疗效观察

Efficacy of kelinao in the treatment of cerebral ischemic injury

目的 观察马来酸桂派齐特注射液（克林奥）治疗缺血性脑损伤的临床疗效。方法将80例缺血性脑血管病人随机分为治疗组和对照组各40例，治疗组用克林奥治疗，对照组用丹参注射液治疗，观察临床疗效和药物不良反应。结果 治疗组总有效率92．5％，明显优于对照组的84．0％（P〈0．05）同时还使病人全血粘度，血浆粘度，纤维蛋白原下降，且未发现明显的副作用。结论 克林奥对缺血性脑损伤的治疗及预防有较好的临床疗效，值得临床推广应用。

Objective To observes the Efficacy of kelinao in the treatment of cerebral ischemic injury. Method 80 stroke patients were randomized into experiment group （treated with kelinao） and control group （treated with dansen）, efficacy and side effects were documented. Results The overall efficacy reached 92.5% in experiment group and 84% in control, with significant difference between the two groups （P〈0.05）, the level of blood plasmas density and fibrinogen significantly decreased after treatment （P〈0.05）. Conclusion kelinao has satisfied efficacy in the treatment of cerebral ischemic stoke with few side effect. It should be widely used in clinic practice.