白细胞介素-6在卵巢癌诊断中的意义

The evaluation if interleukin-6 in diagnosis of ovarian carcinoma

目的探讨白细胞介素-6（IL-6）在卵巢癌诊断中的意义。方法选择卵巢癌患者35例为研究组，卵巢良性肿瘤患者20例和体检健康妇女15例为良性对照组和正常对照组，ELISA法检测血清中IL-6水平。结果研究组血清IL-6水平显著高于卵巢良性肿瘤组和正常对照组（P〈0．05）。研究组中Ⅲ期患者血清中IL-6水平明显高于Ⅰ～Ⅱ期（P〈0．05）。结论IL-6对卵巢癌的诊断有一定的特异性，对分期的判定亦有一定临床意义。

Objective To explore the effect of interleukin-6 in diagnosis of ovarian carcinoma. Methods 35 cases with ovarian carcinoma were selected as study group,and 20 cases with ovarian benign and 15 normal women as control groups. The levels of IL-6 in serum were measured by enzyme-labeled immunosorbent assay（ELISA）. Results The levels of IL-6 in serum in study group were significantly higher than those in control group（ P 〈 0.05）. In study group,the levels of IL-6 in serum in Ⅲ stage were significantly higher than that in Ⅰ～Ⅱ stages（P〈 0.05）. Conclusion IL-6 has much valuable in diagnosis of ovarian carcinoma, and also in determines of clinic stage.