摘要
１４４例临床诊断肺炎的患儿应用酶联免疫吸附试验（ＥＬＩＳＡ）检测柯萨奇Ｂ组病毒（ＣｏｘＢｖｉｒｕｓ，ＣＢＶ）１－６型的感染，检出ＣＢＶ特异性ＩｇＭ阳性２７例，阳性率为１８．７５％，其分型以Ｂ３的阳性率最高，为６２．９０％（１７／２７），以下依次为Ｂ２１８．５０％，Ｂ５１１．１０％，Ｂ４３．７０％，Ｂ３＋Ｂ５３．７０％。ＣＢＶ－ＩｇＭ阳性患儿体液免疫球蛋白ＩｇＡ、ＩｇＧ、ＩｇＭ的检测显示，免疫应答个体反应差异较大，心肌酶谱异常占５９．００％，明显高于阴性组。临床观察病情以轻到中度为主，预防合并症尤为重要。提示ＣＢＶ可引起散发呼吸道感染。
tOnehundredandfortyfourinfantpatientsclinicallydiagnosedaspneumoniaweretestedbyELISAforlgMofCoxsackievirusB1-6(CBV).27(18.75%)outof144infantpatientswereCBV-IgMpositive,amongwhichB3accountedfor62.90%,B214.80%,B511.10%,B43.7%.andB3+B53.70%* ImmunoglobulintestofCBV-IgMpositiveinfantsshowedthattheimmuneresponsedifferedgreatlyamongindividuals.Theabnomtalityofcardiomuscularen-zymereached59.00%* inIgMpositivepatientsthatwasobviouslyhigherthanthatinCBV-IgMnegativegroup.Theclini-calobservationrevealedthattheseverityofthediseasewasmainlyofmildtomedium.Themostimportantistopreventthecomplications.NoticeshouldbetakenthatGBVmaycauserespintorytractinfection.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
1996年第3期237-239,共3页
Chinese Journal of Experimental and Clinical Virology
