邻苯二甲酸-乙酸铜分子印迹聚合物识别性能的研究

Recognition Performance of o-Phthalic Acid-Cu(Ac)_2 Molecular Imprinting Polymers

以邻苯二甲酸与乙酸铜的配合物为模板,在甲醇溶剂中制备印迹聚合物,对其色谱保留行为及结构类似物的识别性能进行了研究.结果表明,在甲醇溶液中,该印迹聚合物不仅能够区分模板分子的结构类似物,而且对配合物的金属阴、阳离子都具有很好的识别作用.以邻苯二甲酸为模板制备的聚合物对模板分子本身的保留较弱,但对模板与铜的配合物却表现出了很强的保留值,在此从结构分析的角度给出了解释.

Molecularly imprinted polymer （MIP） was synthesized by using the complex of o-phthalic acid- Cu（Ac）2 as the template. The experimental results show that Cu（Ac）2-o-PA imprinted polymer [ P（PA/Cu） ] has selective binding to its template complex, including selectivities to the anions, cations and o-PA analogues of the complex. The possible structure of the complex Cu（Ac） 2-o-PA is also proposed according to the crystal structures of similar systems. According to the results, the acetate in Cu （Ac） 2 also participated the imprinting process and is a part of the template. Therefore, it plays an important role in the recognition of template and its analogue complexes. Additiona.lly, the high retention of o-PA-imprinted polymer[ P（PA） ] toward Cu（ Ac）2-o-PA and similar Cu-complexes over o-PA itself is well explained by the binding similarity between 4-VP/o-PA and 4-VP/Cu（Ac） 2-o-PA. The metal ion-mediated imprinting approach of present study may find applications for the compound which can not be directly imprinted.