摘要
目的:评价奥硝唑在治疗厌氧菌感染性牙周疾患中的疗效及全身副反应。方法:采用双盲随机方法选择门诊100例牙周疾患者。其中受试组(奥硝唑)50例和对照组(甲硝唑)50例进行临床治疗对比。观察疗效并记录其副反应进行比较。结果:二者疗效无显著性差异。奥硝唑副反应小,而甲硝唑副反应大,尤其是对胃肠道的刺激性更为显著。结论:奥硝唑对治疗牙周炎效果显著且副作用小于甲硝唑。
Objective：To evaluate the curative effect and systematic side effect of ornidazole in treating infective periodontitis induced by anaerobe, Methods： 100 patients of periodontitis in out - patient clinic were randomly selected and divided into two groups： treatment group with ornidazole and control group with metron- idazole, The curative effect and its side effect were observed and compared, Results： There was no significant difference in curative effect between treatment group and control group. The side effect of metronidazole was more severe than that of or nidazole, especially irritation of gastrointestinal tract, Conclusions：Compared with metronidazole, ornidzole is more effective and safe medicine for periodontitis.
出处
《内蒙古医学杂志》
2006年第7期591-592,共2页
Inner Mongolia Medical Journal
关键词
奥硝唑
甲硝唑
牙周炎
厌氧菌
Oronidazole
Metronidazole
Periodontitis
Anaerobe
