里芋提取物拮抗脂肪分解、促进脂肪合成生理活性研究

BiologicactivetiesofAraceaecolocasiaextractsinhibitedlipolysisandstimulatedlipogenesisinfatcels

目的：对里芋提取物在脂肪代谢中的生理活性进行研究。方法：在体外调制动物脂肪细胞，分别进行脂肪分解和脂肪合成实验，后者用１４Ｃ同位素标记法。结果：有效浓度与生理活性呈一定的正比关系，其活性具不耐热性，有效部分为水溶性物质。结论：里芋含有拮抗肾上腺素诱发的脂肪分解和胰岛素类样作用的物质。

OBJECTIVE:TodealswithbiologicalactivitiesofAraceaecolocasiaextractsonlipolysismetabolism.METHOD:Adrenaline-inducedlipolysisandinsulininducedlipogenesisfrom(U-14C)glucosewereob-servedinfatcelsisolatedfromratepididymaladiposetissue.RESULTS:Araceaecolocasiaextractwasawater-sol-ublesubstanceandshowedtheconcentrationwiththeactivitieslinearly.CONCLUSION:ItisindicatedthatAraceaecolocasiaextractscouldinhibitadrenaline-inducedlipolysisandcouldstimulateinsulin-inducedlipogenesisfromglucoseinfatcels.