实验性肺心病的微循环障碍及其逆转与肺动脉高压的关系

Relationship between the Microcirculation Disturbance and Its Reversion of Experimental Pulmonary Heart Disease and Pulmonary Artery Hypertension

用野百合碱诱发大鼠肺动脉高压后，用中药单体大蒜素进行降压治疗，然后采用胸壁开窗术在活体内观察了降压前后肺表面微循环障碍及其逆转与肺动脉高压的关系。结果表明，肺微循环障碍与肺动脉高压密切相关，并对其发病机制进行了探讨。

Model of pulmonary artery hypertension of the rats was established by monocrobaline,and the animals were treated with garlicin.The relationship between pulmonary microcirculation disturbances before and after hypertension and its reversion and pulmonary artery hypertension was observed with thoracic wall fenestration operation in vivo.The results showed the close relationship between pulmonary microcirculation disturbances and pulmonary artery hypertention.The articles studied the pathogenesis as well.