Endoscopic scoring of late gastrointestinal mucosal damage after adjuvant radiochemotherapy

AIM： To evaluate late effects of chemoradiation on gastrointestinal mucosa with an endoscopic scoring system and compare it to a clinical scoring system. METHODS： Twenty-four patients going to receive chemoradiation after gastric surgery underwent endoscopy four wk after surgery and one year after the chemoradiation finished. Upper gastrointestinal findings were recorded according to a system proposed by World Organisation for Digestive Endoscopy （OMED） and clinical scoring was done with RTOG-EORTC radiation morbidity scoring systems. RESULTS： There was no significant endoscopic difference in gastric and intestinal mucosa after chemoradiation （P 〉 0.05） and there was no association between endoscopic scores and clinical scores. Endoscopic changes were minimal. CONCLUSION： Late effects after chemoradiation in operated patients with gastric cancers can be evaluated with an endoscopic scoring system objectively and this system is superior to clinical scoring systems.

瞄准：与一个内视镜的得分系统在胃肠的粘膜上评估 chemoradiation 的迟了的效果并且把它比作一个临床的得分系统。方法：去在胃的外科以后收到 chemoradiation 的 24 个病人在完成的 chemoradiation 以后在外科和一年以后经历了内视镜检查法四 wk。上面的胃肠的调查结果根据世界组织为消化内视镜检查法(OMED ) 建议的一个系统被记录，临床的得分用完了 RTOG-EORTC 放射病态得分系统。结果：在没有重要内视镜的差别胃并且在 chemoradiation 以后的肠粘膜(P > 0.05 ) 并且在内视镜的分数和临床的分数之间没有协会。内视镜的变化是最小的。结论：在在有胃的癌症的操作病人的 chemoradiation 以后的迟了的效果能客观地与一个内视镜的得分系统被评估，这个系统比临床的得分系统优异。