肺癌患者血清和肺组织中AIF及Ferr含量的测定

DETERMINATION OF ACIDIC ISOFERRITIN AND FERRITIN IN THE SERUM AND CANCER TISSUES OF LUNG CANCER PATIENTS

用放射免疫分析法（ＲＩＡ）检测１６例肺结核、２４例肺炎、３４例肺癌患者的血清酸性异铁蛋白（ＡＩＦ）、铁蛋白（Ｆｅｒｒ）含量，其值分别为１４２．２±８４．５μｇ／ｌ、１０４．２±５９．３ｍｇ／ｌ；１４８．８±７９．５μｇ／ｌ、１０７．３±４６．８ｍｇ／ｌ；２６０．７±１２６．３μｇ／ｌ、１６１．５±７５．３ｍｇ／ｌ。肺癌组ＡＩＦ、Ｆｅｒｒ含量均显著高于对照组（Ｐ＜０．０１），较肺结核组和肺炎组也有显著增高（Ｐ＜０．０１）。因此，推荐血清ＡＩＦ、Ｆｅｒｒ含量作为肺癌特异性诊断的两个血清学指标。

The serum AIF(acidic isoferritin) and Ferr(ferritin) levels are determined for 16 patientg withpulmonary tuberculosis, 24 patinets with pneumonia, 34 patients with lung cancer and 95 normaldonors with RIA method. The rogulng are 142.2±84. 5μg/l & 104. 2±59. 3 mg/l, 148. 8±79. 5μg/l & 107. 3±46. 8 mg/l, 260. 7±126. 3μg/l & 161. 5±75. 3 mg/l, and 103. 8±54. 3μg/l &72. 1±39. 5 mg/l, resepectively. The lung cancer patients group has a remarkably high level as compared with other groups(p<0. 01), waich indicates that the serum AIF & Ferr contents can be usedas important indices in lung cancer diagnosis.