特发性血小板减少性紫癜患者医院感染的危险因素分析

RISK FACTOR ANALYSIS AND PROPHYLAXIS OF HOSPITAL INFECTION AMONG PATIENTS WITH IDIOPATHIC THROMBOEYTOPENIC PURPURA.

目的:探讨特发性血小板减少性紫癜(ITP)患者医院感染危险因素和预防措施。方法:调查住院ITP患者,采用描述流行病学方法对住院感染情况进行分析。结果:医院感染发生率为10.9%,同期医院感染率6.4%。ITR患者医院感染的影响因素包括年龄、性别、激素使用、侵入性治疗、病程、合并其他疾病、贫血、医院感染部位、病原菌。结果:感染部位以肺部为主,病原体多分布于痰液和血液。结论:控制危险因素是预防ITP患者发生医院感染的有效方法。

Objective： To explore the factors and preventive measure of hospital infection among the patients with idiopathic thrombocytopenic purpura. Methods： The clinical information of 634 patients with idiopathic thrombocytopenic purpura were investigated. There were 93 patients with hospital infection （10.9%）. Their ages, sex, PLT amounting, application of adrenocorticosteroid, invasive treatment administrations, hospitalized days, correlated other diseases, anemia, anatonlie area of hospital infection and pathogenic bacteria were collected and evaluated at the same time. Results： The incidence rate of he, spiral infection was higher in patients with idiopathic thrombocytopenic purpura, which was related positively to age, hospitalized days, application Of adrenocorticosteroid, invasive treatment administrations, correlated other diseases and anemia expect for PLT mounting. The most common sites of the hospital infection were lungs, pathogeinic bacteria were mostly distributed in the blood and sputum. Conclusion： In patients with idiopathic thrombocytopenic purpura, the hospital infection is easily induced. So attention must be paid to susceptible factors, in order to effectively prevent hospital infection ,among patients with idiopathic thromboeytopenic purpura.