川芎嗪治疗椎-基底动脉供血不足性眩晕的临床分析

Treatment of vertebro-basilar ischemic vertigo with ligustrazine

目的探讨大剂量川芎嗪注射液治疗椎-基底动脉供血不足性眩晕(VBIV)的临床疗效。方法选择经彩色多普勒血流诊断仪确诊的VBIV患者42例,随机分为两组,治疗组22例给予川芎嗪200mg静脉滴注,对照组20例采用血管扩张剂复方丹参注射液16ml静脉滴注,每日1次,2wk为1疗程,两个疗程后评价疗效。结果治疗组与对照组有效率分别为86.36%和55.00%,两组比较差异有显著性(P<0.05)。结论大剂量川芎嗪治疗椎-基底动脉供血不足性眩晕具有较好的疗效,值得临床推广应用。

Objective To explore the clinical efficacy of Large dosage of ligustrazine on vertebro - basilar isehemie vertigo （VBIV）, Methods 42 VBIV eases diagnosised by color doppler were randomly divided into two groups , the treatmetn group consisted of 22 eases treated with ligustrazine injections and the control group consisted of 20 eases treated with vasodilator salvlac miltiorrhizae Co injectious, one a day for two weeks. The curative effect were compared. Results The total effective rate in the treatment group was 86.36% aud 55.00% in control group, showing significant difference （P 〈 0. 05 ）. Conchlsion Large dosage of Ligustraziue injections is effective for treatment of VBIV and it is worthshile to be popularized for clinical use.