摘要
以5-氨基-3-巯基-1,2,4-三唑和2,6-二氟苯胺为主要原料,经苄基化、环合、酰化、胺解4步反应合成阔草清,总收率46.5%。该方法可以降低成本,提高反应速度,简化分离步骤,降低能耗和减少污染,是一种较清洁的生产工艺,适合工业化生产。
Flumetsulam was synthesized through benzylation cyclization acylation amination using AZT and the cost was decreased. This process could provide a faster reaction rate, a single separation step, lower energy consumption and reduce waste. Thus, it provides a relatively clean production technology which is suitable for industrial scale manufacturing.
出处
《山西化工》
2006年第4期17-18,49,共3页
Shanxi Chemical Industry
关键词
2
6-二氟苯胺
阔草清
除草剂
酰化
合成
2, 6 difluoroaniline
flumetsulam
herbicide
acylation
synthesis
