慢性前列腺炎患者1426例精神障碍调查分析

Epidemiological study on psychological problems of 1426 patients with chronic prostatitis

目的了解慢性前列腺炎(CP)患者精神障碍的患病情况及其相关因素,探讨精神心理因素在CP发病中的作用。方法应用Zung焦虑量表(SAS)和抑郁量表(SDS)、国际前列腺炎症状指数表(NIH-CPSI)、勃起功能指数表(IIEF-5)及自制相关因素调查表对1500例CP患者精神心理状况进行调查。SAS、SDS评分结果与国内正常人测试结果相比较,并分析其与病程、CPSI积分、症状存在时间、性功能状况、年龄、职业、文化程度、前列腺液(EPS)中白细胞数等因素的相关性。结果回收有效问卷1426份(95．07％)。SAS评分42．90±9．67,SDS评分44．24±10．20,均显著高于国内1340名正常人即常模测试结果(SAS 37．23±12．59,SDS 41．88±10．57)(P=0．000)。按SAS≥50、SDS≥53划界,有焦虑症状者337例(23．60%),有抑郁症状者309例(21．7％)。SAS、SDS得分和检出率与病程、CPSI积分、症状存在时间、性功能状况等有相关性(P=0．000),而与年龄、职业、文化程度、EPS中白细胞数无相关性。结论CP患者存在精神心理障碍,并与多种因素有关,精神心理因素在CP发病中具有重要作用。

Objective To investigate the prevalence and the relevant factors of psychological problems of patients with chronic prostatitis （ CP）, and to evaluate the effects of psychological factors on the onset of CP. Methods The Self-Rating Anxiety Scale （SAS） ,Self-Rating Depression Scale （SDS） ,NIH-Chronic Prostatitis Symptom Index （CPSI） , International Index of Erectile Function （ IIEF）-5 and the self-designed questionnaire were employed to investigate the psychological status of 1500 patients with CP. The scores of SAS and SDS were compared with those of the domestic norm of healthy individuals,and then their relevance to such parameters as disease duration, CPSI score, symptom-existing time, sexual function status, age, occupation, educational background and WBC counts in expressed prostatic secretion （EPS） were evaluated. Results The mean ± SD of SAS and SDS were 42.90 ± 9.67 and 44.24 ± 10.20,respectively, both of which were significantly higher than those （SAS,37.23 ±12.59 ;SDS,41.88± 10.57 ;P = 0. 000） of the domestic norm in 1340 healthy controls. If the cut-off points were set at ≥50 （SAS） and ≥53 （SDS） ,337 patients （23.6%） had symptoms of anxiety,and 309 （21.7%） had symptoms of depression. The scores and detection rates of SAS and SDS were correlated with disease duration, CPSI score, symptom-existing time, sexual function status （ P = 0. 000 ） , while they were not correlated with age, occupation, educational background and WBC counts in EPS. Conclusions Psychological problems are common among CP patients and play an important role in the initiation and progression of CP.