286例急性阑尾炎手术患者抗菌药物利用分析

Analysis of Utilization of Antimicrobial Agents in 286 Appendectomy Inpatients

目的:分析急性阑尾炎手术患者的抗菌药利用情况。方法:收集2003—2005年急性阑尾炎手术患者病历286份,采用限定日剂量(DDD)的方法对其抗菌药使用进行统计分析。结果:全部患者在住院期间均使用了抗菌药物,共涉及药物6大类36种,使用最多的是头孢菌素类。多数患者使用了联合用药方案,平均每名患者用了2．77种抗菌药。患者住院期间使用抗菌药时间平均为3．7 d,费用为1 770．95元／例,占药品费用的75．1％。由于选择了不同的药物,抗菌药物日费用表现出明显差异。结论:头孢菌素类药在急性阑尾炎手术患者的抗感染治疗中占居了主导地位,适当缩短用药时间,选择日均治疗费用较低的药品可有效降低患者的住院费用。

Objective： To analyze the utilization of antimicrobial gents in appendectomy patients. Method： 286 appendectomy inpatients were chosen and analyzed from 2003 to 2005. The utilization of antimicrobial agents was evaluated by using the defined daily doses（DDD） method. Result： Antimicrobial agents were prescribed to all the patients. There were 36 kinds of drugs belonging to 6 classes used by 286 cases, in which cephalosporins were administrated most. The combination schemes were used by the great majority （2.77 kinds per case）. The antimicrobial therapy lasted 3.7 days averagely. The average antibiotics cost was 1770.95 yuan per case, which was 75.1% of the total drug fees. The drug fee per day showed a significant difference due to the varied choice of antimicrobial agents. Conclusion： Cephalosporins were the most important drugs in clinical anti - infection therapy. The hospitalization expenses in appendectomy patients could be well controlled if the period of treatment was shortened and the cheaper drugs were selected.