舒筋通络颗粒治疗神经根型和椎动脉型颈椎病Ⅱ期临床研究

The II Clinical Study of Shujintongluo Keli Treating the Cervical Spondylosis With the Nerve root type and Vertebral artery type

目的:观察舒筋通络颗粒(曾用名:复方牛膝颗粒)治疗神经根型和椎动脉型颈椎病(中医辨证属于肝肾亏损,气虚血瘀证候者)的临床疗效,并考察其安全性。方法:250例患者通过多中心随机双盲对照试验的方法进行临床试验,试验病例为126例。结果:神经根型颈椎病患者治疗组总有效率为90.8%,对照组总有效率为93.5%,两组比较差异无显著性意义。椎动脉型颈椎病患者治疗组总有效率为95.1%,对照组总有效率为85.2%。两组比较,差异无显著性意义。两组治疗后主要临床症状、体征均有明显改善。结论:舒筋通络颗粒治疗能明显改善患者的主要临床症状、体征,治疗颈椎病神经根型及椎动脉型临床疗效与对照药相当。可用于神经根型颈椎病及椎动脉型颈椎病中医辨证属于肝肾亏虚、气虚血瘀证患者的临床治疗。

Objective：To observe the clinical effect and the safety of Shujintongluo Keli in treatment of the Cervical Spondylosis With the Nerve root type and the Vertebral artery type. Metlaods：Two hundred and fifty eases of the Cervical Spondylosis were grouped randomly into the treatment group and control group,and the treatment group has 126 cases. Resells：the Nerve root type＇s curative ratio of treatment group was 90.3 %,and the control group was 93.5 %; the Vertebral artery type＇s curative ratio of treatment group was 95.1%, and the control group was 85.2 %, there was significant difference between two groups by statistical analysis. Conclusions：Shujintongluo Keli can release the eases clinical symptom. It can treat the Cervical Spondylosis With the Nerve root type and Vertebral artery type belong to efficiency of liver and kidney, efficiency of qi and blood stasis.