左旋卡尼汀能有效提高稳定型心绞痛患者的运动耐量

L-carnitine effectively improves exercise tolerance in patients with stable angina pectoris

目的观察国产左旋卡尼汀(L-CN)对稳定型心绞痛患者临床症状和运动耐量的影响。方法在常规治疗的基础上使用L-CN辅助治疗稳定型心绞痛患者80例,40例患者作为对照。记录两组患者治疗前后临床症状、心电图、心功能、运动试验心电图。结果L-CN可以明显缓解患者心绞痛临床症状,改善心功能,并显著提高运动耐量和心绞痛负荷阈值。结论L-CN是心绞痛代谢治疗的有效药物之一。

AIM To investigate the effect of L-carnitine （L-CN） on the clinical symptoms and exercise tolerance in patients with stable angina pectofis. METHODS Clinical symptoms, ECG, heart function and exercise tolerance of 80 patients with stable angina pectoris were measured before and after they received L-CN 3.0 g intravenous infusion per day for 21 d, and 40 other patients were included as control. RESULTS L-CN alleviated clinical symptoms, and improved heart function and exercise tolerance of patients. CONCLUSION L-CN is one of the effective metabolitic drugs for stable angina pectoris.