血清高敏C反应蛋白与急性冠脉综合征的相关性

Correlation between serum high sensitive c-reactive proteins and acute coronary syndrome

目的研究血清高敏C反应蛋白(hsCRP)与急性冠脉综合征(ACS)的相关性及其相关因素。方法用速率散射光比浊法检测了56例冠心病患者(13例稳定型心绞痛,17例不稳定型心绞痛,26例急性心肌梗死)不同类型冠心病患者血清hsCRP水平。结果ACS组(含不稳定型心绞痛和急性心肌梗死)血清hsCRP水平(7.1±8.1)mg/L显著高于稳定型心绞痛组(1.5±1.1)mg/L(P<0.01);ACS危险因子多因素Logistic回归分析显示,hsCRP与ACS呈正相关(P<0.05)。结论ACS患者血清hsCRP水平显著增高。hsCRP水平与ACS呈正相关。

AIM To study the relationship between serum high sensitive c-reactive protein and acute coronary syndrome. METHODS The levels of serum high sensitive c-reactive （hs-CRP） were measured in 56 patients with coronary heart disease （CHD） , including 13 cases of stable angina pectoris （SAP） , 17 cases of unstable angina pectoris （UAP） and 26 cases of acute myocardial infarction （AMI）. The serum hs-CRP levels were then compared among different types of CHD. RESULTS The serum hs-CRP levels （7.1 ± 8.1 ） mg/L were significantly higher in the ACS group, including UAP group and AMI group, than those （1.5 ± 1.1 ）mg/L in the SAP group （P 〈0.01 ）. Logistic regression analysis showed that hs- CRP levels were positively related to ACS （P 〈 0.05）. CONCLUSION The serum hs-CRP levels are significantly higher in the patients with ACS. hs-CRP levels are positively related to ACS.