摘要
目的研究血清中P物质和降钙素基因相关肽在慢性荨麻疹中的作用。方法对24例慢性荨麻疹患者,采用ELISA法测定血清P物质和降钙素基因相关肽水平,并与正常人对照组(n=21)进行比较。结果慢性荨麻疹患者血清中P物质和降钙素基因相关肽浓度分别为(102.47±8.02)ng/L、(83.72±5.97)ng/L,均较正常对照组显著升高(P<0.05)。结论血清P物质和降钙素基因相关肽在慢性荨麻疹的发病中发挥了一定作用。
Objective To investigate the role of substance P（SP） and calcitonin gene-related peptide（CGRP） in chronic urticaria patients. Methods ELISA was used to test serum SP and CGRP levels in 24 patients with chronic urticaria and 21 norreal controls. Results The serum SP and CGRP levels were（102. 47 ± 8. 02）ng/L, （83. 72 ± 5.97）ng/L respectively, both significantly higher than that of normal controls（P〈0. 05）. Conclusion SP and CGRP may play an important role in the pathogenesis of chronic urticaria.
出处
《华中医学杂志》
2006年第4期286-287,共2页
Central China Medical Journal
关键词
荨麻疹
P物质
降钙素基因相关肽
Urticaria
Substance P
Calcitonin gene-related peptide
