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地氯雷他啶治疗人工性荨麻疹临床观察 被引量:1

Clinical observation of desloratadine in the therapy of factitious urticaria.
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摘要 目的观察地氯雷他啶(恩理思)治疗人工性荨麻疹的疗效和安全性。方法32例人工性荨麻疹患者均服用恩理思片。每天1次,每次5mg。每服用12天左右,根据病情好转情况,适当减量。结果32例中痊愈17例,显效6例,进步5例,无效4例,有效率为71.9%。全部病例均未发生明显不良反应。结论采用恩理思治疗是一种治疗人工性荨麻疹的好方法,值得临床推广。 Objective To survey the therapeutic effects and reliability of Desloratadine (Aerius) in the treatment of factitious urticaria. Methods Thirty-two patients with factitious urticaria took Aerius tablets, 5 mg, once every day, 12 days. The dose was adjusted according to the patients condition. Results Seventeen cases were cured, 6 cases obtained significantly improvement, 5 cases progress, and 4 cases inefficient with the effective rate being 71.9%. No obvious side effects occurred. Conclusion Aerius is a kind of effective and safe drug to factitious urticaria.
作者 李慎秋
出处 《华中医学杂志》 2006年第4期290-291,共2页 Central China Medical Journal
关键词 荨麻疹 恩理思 地氯雷他啶 疗效观察 Urticaria Aerius Desloratadine Clinical observation
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  • 1Kreutner W, Hey JA, Chiu P et al. Preelinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication:lack of central nervous system and cardiovascular effects.Arzneimittelforschung, 2000,50(5) :441
  • 2Kreutner W, Hey JA, Anthes J et al. Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication:receptor selectivity, antihistaminic activity, and antiallergenic effects. Arzneimittelforschung, 2000,50(4) : 345
  • 3Schroeder JT, Schleimer RP, Lichtenstein LM et al. Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy, 2001,31(9):1369
  • 4Molet S, Cosset P, Lassalle P et al. Inhibitory activity of loratadine and descarboxyethoxyloratadine on histamine-induced activation of endothelial cells. Clin Exp Allergy, 1997,27(10) : 1167

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