抑郁障碍与心肌梗死的研究进展

The Progress of Depressive Disorder and Myocardial Infarction

抑郁障碍对心肌梗死患者的发生、发展及预后存在负性影响。抑郁障碍可通过影响生活方式、血小板活性、内皮功能,引起炎性反应、自主神经功能障碍,加重心功能不全等方面引起心肌梗死患者病残、病死率增加。对于合并抑郁障碍的心肌梗死患者进行临床干预非常重要,心理治疗、药物治疗可能可以改善此类患者预后。

Depressive disorder have adverse effect on the patients with MI about its genensis, development and prognosis. It can also result in inflammatory reaction and dysautonomia and aggravate cardia insufficiency by influencing life style ,activity of platelet and endothelial function,which then result in the increase of patients＇ disability rate and case fatality. It is very important to carry clinical intervention on the patients with MI combined with depressive disorder, in which psychotherapy and drug treatment can promote the prognosis of this kind of patients.