肾虚型多囊卵巢综合征与血清T、LH的相关性研究

Research of the Relationship Between T,LH and Kideny-Deficiency Polycystic Ovary Syndrome

目的探讨多囊卵巢综合征(PCOS)患者肾阴虚证、肾气虚证与睾酮(T)、黄体生成激素(LH)之间的关系。方法将58例PCOS患者辨证分为3组:肾阴虚证组24例,肾气虚证组20例,非肾虚证组14例;另选取正常对照组19例,检测各组患者T、LH水平,比较组间的差异。结果①T水平:肾阴虚证组>肾气虚证组>非肾虚证组>正常对照组;其中肾阴虚证组与其他三组间存在非常显著性差异(P<0.01);而其他组两两比较未见显著性差异(P>0.05)。②血清LH水平、LH/FSH比值:肾气虚证组>肾阴虚证组>非肾虚证组;肾气虚证组与肾阴虚证组、非肾虚证组间比较存在显著性差异(P<0.05);肾阴虚证组和非肾虚证组间比较未见显著性差异(P>0.05)。结论T水平增高与PCOS肾阴虚证有关;血清LH水平、LH/FSH比值增高与PCOS肾气虚证有关。

Objective To explore the relationship between kidney-yin,kidney-qi deficiency syndrome and T, LH of polycystic ovary syndrome. Methods According to differentiation diagnosis standard of TCM, 58 PCOS patients were divided into three groups： 24 PCOS patients with kidney-gin deficiency syndrome（SYDS）, 20 PCOS patients with kidney-qi deficiency syndrome（SQDS）, and 14 PCOS patients without kidney deficiency syndromes （non-kidney deficiency syndromes, NSDS）. Moreover, 19 normal persons were selected as the controls group. In order to compare the difference of reproductive hormone among the groups, serum T, LH were tested. Results ①The serum T level of PCOS patients with SYDS was significantly higher than SQDS group, NSDS group and the control group（P〈 0.01）.Pairwise comparisons of other groups have not seen the remarkable difference （P〉 0.05）. ②The serum LH level and the LH/FSH ratio of PCOS with SQDS were significantly higher than SYDS group, NSDS group（P〈 0.05）. Comparison of SYDS group and NSDS group has not seen the remarkable difference （P〉0.05）. Conclusions The increase of serum T maybe correlates with SYDS in PCOS. The increase of LH and LH/FSH maybe correlates with SQDS in PCOS.