摘要
396例活检胃粘膜炎症性病变中19.9%找见异型增生灶,其由单个至10多个细胞构成,可向管腔内或外突起。其检出率为糜烂性胃炎的8.0%,浅表性胃炎的10.9%,萎缩性胃炎的38.4%,慢性溃疡的18.9%。灶性异型增生细胞PCNA阳性表达61.3%;AgNOR计数3.81~8.72个,提示PCNA和AgNOR检测可帮助判断胃粘膜灶性异型增生。
cases of biopsied gastric mucosa with inflammation were studied pathologically. Focal dysplasia was found in 19.9% of the cases. Most of the foci consisted of 1-10 cells. The detectable rate of focal dysplasia was 8.0% in erosive gastritis,10. 9% in superficial gastritis,38.4% in atrophic gastritis and 18. 9% in chronic gastric ulcer.The positive rate of PCNA(proliferating cell nuclear antigen)in the focal dysplastic cells reached 61.3%.The count of AgNOR(nucleolar organizer regions) was between 3.81-8. 72.It indicates that the detection of PCNA and AgNOR might be helpful in the diagnosis of focal dysplasia of gastric mucosa.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1996年第9期657-658,共2页
Chinese Journal of Clinical Oncology