不同时机气管内冲洗治疗羊水Ⅲ度污染新生儿146例疗效分析

The analysis on therapeutic effect of endotracheal wash for neonates with severe meconium-stained fluid during different period

目的探讨不同时机气管内冲洗治疗对羊水Ⅲ度污染新生儿疗效的影响。方法将符合病例选择标准的146例患儿分为三组,A组49例于出生时即刻进行气管插管冲洗,B组54例,C组43例分别于生后6 h内和6~12 h行气管插管冲洗。治疗3天后比较三组疗效。结果A、B组的MAS发生率分别为20.41%和40.74%,两组MAS的发生率显著低于C组的69.77%(P均<0.017)。治疗3天后比较,A组疗效较好。结论对Ⅲ度羊水污染新生儿尽早进行气管内冲洗能有效降低MAS的发生率,提高治疗效果。

Objective To investigate the therapeutic effect of endotracheal wash for neonates with severe meconium-stained fluid during different period. Methods 146 neonates with severe meconium-stained fluid were divided into three groups. 49cases （group A） were given endotracheal wash after birth. 54 cases （group B） and 43 cases （group C） were given endotracheal wash 6 hours and 6 to 12 hours after birth respectively. Their therapeutic effects were compared three days after treatment. Results The incidence rate of MAS in group A and group B were 20. 41% and 40. 74% respectively,They were lower than the rate of group C 69.77%（ P 〈0. 017）. The comparison of thr^e days after treatment shown that the effect of group A was better than others. Conclusion Endotracheal wash could decrease the incidence rate of MAS and improve the effect of the treatment.