基底核钙化30例

Thirty Cases with Basal Ganglia Calcification

目的探讨儿童基底核钙化(BGC)的相关疾病、主要病因和临床特点。方法对CT和检查发现的30例儿童BGC的临床资料进行回顾性分析,总结儿童BGC的临床表现、影像学特点。结果多种因素、疾病与儿童BGC相关,如甲状旁腺功能减退、宫内感染和缺氧、癫、外伤后腔隙性脑梗死等。临床主要表现为抽搐、精神运动发育迟缓、肢体运动障碍等。CT上表现为基底核区局限性点状钙化。结论儿童BGC的临床表现多样。对头颅CT发现的BGC儿童进一步确诊病因,未能确诊病因的BGC儿童应加强随访。

Objective To explore the related diseases, main causes and clinical features of children with basal ganglia calcification （BGC）. Methods Thirty cases with BGC detected by CT were studied retorspectively,and its clinical symptoms and image were summarized. Results Many factors and diseases were related to BGC, such as hypothyroidism, intrauterine infection, intrauterine hypoxia, epilepsy, posttraumatic cerebral lacunar infarction. Main clinical manifestations of BGC in children were twich, mental retardation, disorders of limb movements etc. The CT scan showed localized punctuate calcification in basal ganglia. Conclusions The main causes of BGC in children are hypothyroidism, intrauterine infection and intrauterine hypoxia,and the clinical manifestations are diverse. For children with CT-detected BGC should diagnose its causes;and for unknown causes cases should strengthen follow-up,