引导组织胶原膜在乳突根治术中的应用

Application of the collagen in mastoidectomy

目的：观察乳突根治术后，应用引导组织胶原膜对乳突腔愈合的影响。方法：41例胆脂瘤中耳炎患者行开放式乳突根治术，其中22例应用胶原膜加游离薄皮片（应用组）处理乳突术腔；19例只用游离皮片（未应用组）。术后随访，对比观察术腔愈合情况和上皮化时间。结果：应用组肉芽生长少，无复发，术腔上皮化时间为3～7周，平均（4．5±0．7）周；未应用组肉芽生长多，复发1例，术腔上皮化时间为5～12周，平均（7．2±0．8）周。对2组术腔上皮化时间行统计学检验，差异有统计学意义（P〈0．01）。结论：医用胶原膜可促进上皮组织再生，减少术后感染及肉芽发生，加速乳突腔上皮化，提高乳突根治术疗效。

Objective：To evaluate the effect of the collage application in mastoidectomy. Method：Forty-one patients （41 ears） with chronic suppurative otitis media （choleseatoma type） were surgically treated by mastiodectomy, in which 22 cases （22 ears） used collagen and dissociative flap to deal with mastoid cavity but 19 cases （19 ears） without collagen. All patients were followed up for one year to observe the situation after mastiodectomy comparatively. Result：The epithelization time of mastoid cavity was 3 to 7 weeks, averaging （4.5±0.7） weeks in the collagen-applying group and was 5 to 12 weeks, averaging （7.2±0.8） weeks in control group. The epithelization time was significantly different between these two groups（ P〈0. 01）. Conclusion： The collagen can reduce infection and promote epithelization of mastoid cavity after mastiodectomy, which is clinically worthy to be applicated in mastiodectomy.