摘要
瞄准：估计发生并且在 Kinmen 在类型 2 糖尿病患者之中为胆石疾病(GSD ) 冒因素的风险，台湾。方法：为 GSD 的一个屏蔽节目被采用了即时腹的超声在病人们有 fasted 至少八个小时以后，检验腹的区域的二位专家执行。屏蔽，它在 2001 被进行，包含了与类型 2 糖尿病诊断的 848 个病人。在有流行 GSD 的 63 个题目的排除以后，没有 GSD 的 377 个参加者为秒轮屏蔽在 2002 被邀请。281 的一个总数(74.5%) 使遭到是 re-examined。结果：在 281 类型之中没在首先屏蔽有 GSD 的 2 名糖尿病患者， 10 在 2002 开发了 GSD。发生每年是 3.56%(95% CI：1.78% 每 year-6.24% 每年) 。用一个考克斯回归模型，变老(RR = 1.07， 95% CI：1.00-1.14 ) ，腰圆周(RR = 1.12， 95% CI：1.01-1.29 ) ，并且中高音(RR = 1.13， 95%CI：1.01-1.26 ) 看起来显著地与 GSD 的开发被相关。结论：老年是为 GSD 的发展的一个已知的风险因素。我们那更大的腰圆周和提高的中高音铺平的学习表演也在 Kinmen 在类型 2 糖尿病患者之中与 GSD 的发展被联系。
AIM： To assess the incidence of and risk factors for gallstone disease （GSD） among type 2 diabetics in Kinmen, Taiwan. METHODS： A screening program for GSD was performed by two specialists who employed real-time abdominal ultrasound to examine the abdominal region after patients had fasted for at least eight hours. Screening, which was conducted in 2001, involved 848 patients diagnosed with type 2 diabetes. After exclusion of 63 subjects with prevalent GSD, 377 participants without GSD were invited in 2002 for a second round of screening. A total of 281 （74.5%） subjects were re-examined. RESULTS： Among the 281 type 2 diabetics who had no GSD at the first screening, 10 had developed GSD by 2002. The incidence was 3.56% per year （95%CI： 1.78% per year-6.24% per year）. Using a Cox regression model, age （RR = 1.07, 95% CI： 1.00-1.14）, waist circumference （RR = 1.12, 95% CI： 1.01-1.29）, and ALT （RR = 1.13, 95%CI： 1.01-1.26） appeared to be significantly correlated with development of GSD. CONCLUSION： Older age is a known risk factor for the development of GSD. Our study shows that greater waist circumference and elevated ALT levels are also associated with the development of GSD among type 2 diabetics in Kinmen.
基金
Supported by the grants from the Cheng Hsin Rehabilitation Medical Center, No. 93-25
关键词
胆结石
糖尿病
并发症
治疗
Type 2 diabetes
Gallstone disease
Incidence density
Population-based study
