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肉碱与男性生殖 被引量:44

Carnitines and Male Reproduction
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摘要 肉碱是机体内重要的条件必需营养素,具有广泛的生理作用。男性附睾与精子中含有体内最高浓度的肉碱,肉碱不仅在启动精子运动、促进精子成熟和提高精子受精能力等方面具有重要作用,而且在调节Sertoli细胞功能、保护精子对抗氧化损伤、减少生精细胞凋亡、抑制精子聚集等方面具有重要意义。本文就肉碱在男性生殖中的作用做一综述。 Carnitines are important conditionally essential nutrients in the organism, with extensive physiological functions, and highly concentrated in the epididymis and sperm. Carnitines play an important role not only in initiating sperm motility, promoting sperm maturation and enhancing sperm fertilizing, but also in regulating Sertoli cell function, protecting sperm against oxidative damage, reducing apoptosis of spermatogenic cell and inhibiting sperm aggregation. Accordingly, the objective of this review is to summarize the multifunctional roles of camitine in male reproduction.
出处 《中华男科学杂志》 CAS CSCD 2006年第8期726-729,共4页 National Journal of Andrology
基金 江苏省"六大人才高峰"资助项目(2005A5)
关键词 肉碱 睾丸 附睾 精子 SERTOLI细胞 carnitine testis epididymis sperm Sertoli cell
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参考文献27

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