唾液SIgA、溶菌酶含量与慢性支气管炎关系的探讨

Study on the Salivary Contents of Secretory Immunoglobulin A(SIgA) and Lysome(Lys) in Patients with Chronic Bronchitis

目的:探讨了慢性支气管炎患者唾液SIgA和溶菌酶含量的变化及临床意义。方法:应用放射免疫分析检测38例慢性支气管炎患者唾液SIgA含量,免疫扩散法测定溶菌酶含量,并与35名正常人作比较。结果:慢性支气管炎患者唾液SIgA和溶菌酶含量非常显著地高于正常人组(P<0.01),经2周治疗后仍有显著性差异(P<0.05)。结论:检测慢性支气管炎患者唾液SIgA和溶菌酶含量的变化对临床观察预后有重要的临床价值。

Objective To study the sailic levels of SIgA and lys in patients with chronic bronchitis. Methods Sailic SIgA （with RIA） and lys （with immunodiffusionassay） levels were measured in 38 patients with chronic bronchitis both before and after treatment as well as in 35 controls. Results Before treatment the saliae SIgA and lys levels in the patients were significantly higher than those in controls （P 〈0.01 ）. After treatment for 2 weeks, the sailie SIgA and lys levels, though dropped markedly, remained significantly higher than those in controls （ P 〈 0.05 ）. Conclusion Changes of sailie SIgA and lys levels content after treatment might be of prognostic importance in patients with chronic bronchitis.