AMI患者cTnI和CRP水平的变化

Change of Plasma cTnI and Serum CRP Levels in Patients with AMI

目的:测定急性心肌梗死(AM I)患者血浆cTnI和血清CRP水平及探讨其临床意义。方法:采用化学发光、免疫比浊分析法观察了30例AM I患者和30例健康者血浆cTnI和血清CRP水平。结果:①30例AM I患者cTnI浓度(26.52±14.92)ng/m l,30例健康者血浆cTnI浓度为(0.11±0.034)ng/m l,两组比较差异非常显著(P<0.001)。②30例AM I患者血清CRP浓度为(55.39±50.78)mg/L,30例健康者血清CRP浓度为(1.01±0.26)mg/L,两组比较差异非常显著(P<0.001)。③30例AM I患者血浆cTnI与血清CRP呈正相关(r=0.291)。结论:cTnI和CRP水平对判断AM I的预后是一个有效的指标。

Objective To explore the clinical signficance of changes of plasma troponin Ⅰ （cTnⅠ） and serum C reactive protein （CRP） levels in patients with acute mycardial infarction （AMI）. Methods Plasma cTnI （with chemiluminescence assay） and the serum CRP （ with immune turbidity method） were measured in 30 patients with AMI and 30 controls. Results （ 1 ） The plasma levels of cTnI in patients with AMI （26.52±14.92） ng/ml, were significantly higher than those in controls （0.11±0. 034ng/ml, P 〈0. 001 ）. （2） The serum levels of CRP in AMI patients （55.39±50.78）mg/L, were also significantly higher than those in controls （ 1. 01±0.66mg/L, P 〈 0. 001 ）. （3） cTnI and CRP levels were mutually positively corelated （r = 0. 291 ）. Conclusion The levels of cTnI and CRP are useful markers to predict the prognosis of AMI.