中晚期周围型肺癌临床分期病理分型与中医证型相关性研究

Comparative Study between the Differentiation of TCM Syndrome and the Clinical Stage Histopathology about Peripheral Pulmonary Carcinoma in Intermediate and Advanced Stage

目的:研究中晚期原发性周围型肺癌临床分期、病理分型与中医临床证型的相关性。方法:收集56例中晚期原发性周围型肺癌(以下简称肺癌)肺癌临床分期、组织病理学类型及中医临床证型资料,按照中医辨证分组:分为肺郁痰瘀、脾虚痰湿、阴虚痰热、气阴两虚4种证型,研究临床分期、组织病理学类型与各中医证型间的相关性。结果:4种证型中以肺郁痰瘀型多见(37.5%)。不同中医证型的病理类型具有统计学意义(P<0.05);肺郁痰瘀型以鳞癌多见;脾虚痰湿型以肺泡癌多见;阴虚痰热型以腺癌多见;不同临床分期的中医证型不具有统计学意义(P<0.05)。结论:原发性周围型肺癌组织病理学与中医证型之间存在着一定的内在关系。

Objective： To study the correlation between Traditional Chinese Medicine （TCM）differentiation of syndromes of primarily Peripheral Pulmonary Carcinoma （PPC） inintermediate and advanced stage and the clinical stage, histopathology. Methods： We retrospectively reviewed the clinical records and histopathology of 56 patients with TCM differentiation, namely, Feiyutanyu, Pixutanshi, Yinxutanre, Qiyinliangxu. Their relations were analyzed. Results： Feiyutanyu were more common in six TCM differentiation. Squamous carcinoma was more common in Feiyutanyu TCM differentiation. Alveolar cell carcinoma was more common in Pixutanshi TCM differentiation. Adenocarcinoma was more common in Yinxutanre TCM differentiation. Conclusion： TCM differentiations of syndromes of PPC have relations with histopathology.