脑电超慢涨落技术分析强迫症治疗前后脑内神经递质的变化及意义

The Therapeutic Changes of Brain Neurotransmitters in Obsession

目的:用脑电超慢涨落分析仪(ET)检测强迫症患者治疗前后脑内神经递质的变化。方法:对入组标准的40例患者用脑电超慢涨落分析仪在治疗前后的不同阶段对神经递质含量进行检测。结果:强迫症患者脑内神经递质5-羟色胺(5-HT)及去甲肾上腺素(NE)的变化,与其临床症状的严重程度和治疗效果变化相一致。结论:ET检测脑内神经递质在强迫症中随疾病恢复的动态变化,可作为判断疗效、治疗安全性的依据。

Objective： To observe the changes of brain neurotransmitters in obsession before and after treatment. Methods： The level of neurotransmitters of 30 patients with obsession was measured by the Encephalofluctuograph technology before and after treatment. Results： The neurotransmitter＇s levels were declined, special in 5 - HT and NE. The therapeutic changes of neurotransmitters were significantly correlated with the efficacy. Conclusion： The levels of 5 - HT and NE were significantly reduced and increased gradually with the treatment and recover.