摘要
在敏感株和阿霉素耐药株ＭＣＦ－７和ＭＣＦ－７／Ａｄ以及敏感株和长春新碱耐药株ＫＢ和ＫＢｖ２００两种人癌细胞的体外试验中，发现汉防己甲素对耐药细胞株的ＭＣＦ－７／Ａｄ具有明显的选择性作用。
In an in vitro culture system of human cancer cells MCF 7 and its adriamycin resistant line MCF 7/Ad or KB and its vincristine resistant line KBv 200 ,tetrandrine was found to exhibit significantly selective anticancer activity against the drug resistant cancer cell MCF 7/Ad.In addition,essentially complete reversal effects of tetrandrine on drug resistance were observed in MCF/Ad or KBv 200 .
出处
《中国中药杂志》
CAS
CSCD
北大核心
1996年第6期369-371,共3页
China Journal of Chinese Materia Medica
关键词
汉防己甲素
阿霉素
长春新碱
肿瘤
抗药性
tetrandrine,adriamycin,vincristine,KB cell,MCF 7 cell (original article on page 369)
