期刊文献+

BCL-2/BAX P^(53) C-MYC在肾盂、输尿管肿瘤中的表达及意义

下载PDF
导出
摘要 BCL-2/BAX P53、CMYC等基因为原癌基因,本文就上述基因分子生物学特性及作用机制,对细胞周期的影响、该类基因缺陷与肿瘤的关系及在肾盂、输尿管肿瘤的表达和意义加以概述。
出处 《黑龙江医学》 2006年第7期505-506,共2页 Heilongjiang Medical Journal
  • 相关文献

参考文献15

  • 1Levine B,Huang Q,Isaacs J T.Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene[J].Nature,1993,25;361(6414):739~42.
  • 2Oltvai Z N,Milliman C L,Korsmeyer S J.Bcl-2 heterodimerizes in vivo with a conserved homolog,Bax,that accelerates programmed cell death[J].Cell,1993,27;74(4):609~19.
  • 3赵忠文 许宁 石爱平 等.肾癌细胞凋亡率与c—myc表达分布及其临床意义[J].中华泌尿外科学杂志,1998,8:196-199.
  • 4Elliott K,Ge K,Du W,et al.The c-myc-interacting adaptor protein bin1 activates a caspase-independent cell death program[J].Oncogene,2000,19(41):4 669~84.
  • 5HermekingH EickD.Mediation of c—Myc—induced apoptosis by P53[J].Science,1994,265(5181):2091-3.
  • 6Miyashita T,Harigai M,Hanada M,et al.Identification of a P53-dependent negative response element in the bcl-2 gene[J].Cancer Res,1994,54(12):3 131~5.
  • 7Ryan J J,Prochownik E,Gottlieb C A,et al.C-myc and bcl-2 modulate P53 function by altering P53 subcellular trafficking during the cell cycle[J].Proc Natl Acad Sci USA,1994,91(13):5 878~82.
  • 8Vaux D L,Cory S,Adams J M.Bc1-2 gene promotes haemopoietic cell survivaland cooperates with c-myc to immortalize pre-B cells[J].Nature,1988,335(6189):440~2.
  • 9Lee C C,Wanibuchi H,Yamamoto S,et al.Molecularcytogenetic identification of cyclin D1 gene amplification in a renal pelvic tumor attributed to phenacetin abuse[J].Pathol Int,1999,49(7):648~52.
  • 10Yu D S,Chang S Y.The expression of oncoproteins in transitional cell carcinoma:its correlation with pathologicalbehavior,cell cycle and drug resistance[J].Urol Int,2002,69(1):46~50.

二级参考文献7

  • 1种铁,国外医学泌尿系统分册,1995年,15卷,110页
  • 2FraleyEE.Canceroftherenalpelvis[].Genitouri naryCancer.1978
  • 3Huben RP,Mounzer AM,Murphy GP.Tumor grade and stage as prognostic variables in upper urothelial tumors[].Cancer.1988
  • 4Masuda M,Takano Y,Iki M,et al.Apoptosis in transitional cell carcinoma of the renal pelvis and ureter: association with proliferative activity, Bcl-2 expression and prognosis[].Journal d Urologie.1997
  • 5Furihata M,Sonobe H,Ohtsuki Y,et al.Detection of p53 and Bcl-2 protein in carcinoma of the renal pelvis and ureter including dysplasia[].Journal of Paleopathology.1996
  • 6Terrell RB,Cheville JC,William AS,et al.Histopathological features and p53 nuclear protein staining as predictors of survival and tumor recurrence in patients with transitional cell carcinoma of the renal pelvis[].Journal d Urologie.1995
  • 7Rey A,Lara PC,Redondo E,et al.Overexpression of p53 in transitional cell carcinoma of the renal pelvis and ureter.Relation to tumor proliferation and survival[].Cancer.1997

共引文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部