摘要
目的筛查儿童佝偻病发生情况,探讨骨源性碱性磷酸酶在儿童佝偻病诊断中的价值,以降低漏诊率,提高治疗效果。方法选取佝偻病患病组和随机抽取对照组进行骨源性碱性磷酸酶测定。结果骨源性碱性磷酸酶在对照组中≤200U/L的儿童占51．5%,而患病组中≤200U/L的儿童仅占3．9%,患病儿童中96．1%的儿童骨源性碱性磷酸酶＞200U/L,且患儿病情越重,骨源性碱性磷酸酶活性越高。结论骨源性碱性磷酸酶的测定,为儿童佝偻病的诊断提供了有价值的手段。同时也提示,本地区佝偻病发生率仍很高,应引起高度重视。
Objective To investigate morbidity of children＇s rickets in our district and to evaluate clinical value of detection of bone alkaline phosphatase for diagnosis of rickets so as to decrease the missed diagnosis rate and improve therapeutic effect of the disease. Methods Bone alkaline phosphatase was detected with NBAP KIT（ produced by ZS-Kingmed） for children with rickets and normal children as controls who were selected randomly. Results BAP value of 3.9 % of children with rickets was 〈200U/L, while that of 51.5 of normal control children was 〈200U/L. BAP value of 96.1% of children with tickets was 〉200U/L, and the more severe the children＇s rickets, the higher the activity of BAP. Conclusion Detection of bone alkaline phosphatase provides a valuable means for diagnosis of rickets. Meanwhile, it suggested that the prevalence of rickets among children is high in this district and more attention should be paid.
出处
《中国妇幼健康研究》
2006年第4期273-274,共2页
Chinese Journal of Woman and Child Health Research
