摘要
子宫内膜异位症是一种妇科多发病,发病机制仍不清楚,临床上至今还缺乏用于诊断的有效生化标志物。子宫内膜异位症患者体内有许多生化分子的表达发生变化,其与子宫内膜异位症的发生、发展有关,如CA-125、CA19-9、抗子宫内膜抗体等,目前已经是内异症诊断的重要辅助手段。其它分子,如白细胞介素、黏附分子、肿瘤坏死因子、生长因子等在血清或腹腔液中的浓度也发生改变,研究这些变化与内异症的关系可以提示这些生化分子的临床应用价值,为内异症的诊断提供更简便、更易普及的血清学检测方法。
Endometriosis （EMs） is a common and frequent gynecopathy. Its pathogenesis is unclear till now. No effective biochemical markers that can be used to diagnose endometriosis are available in clinical work. Many researches showed that the expression of various biochemical molecules changes in patients with endometriosis. These molecules such as CA-125, CA19-9 and EMAb are associated with occurrence and development of EMs. Detection for them has become an auxiliary method in the diagnosis of EMs. Also the concentrations of some other molecules in serum or abdominal fluid such as interleukin, adhesion molecule, TNF, growth factor and so on change in the patients with endometriosis, which reveals the clinical value of these molecules by researching the relationship between these changes and EMS, so as to provide a more convenient and popular serologicaUy diagnosing method for EMs.
出处
《中国妇幼健康研究》
2006年第4期327-329,共3页
Chinese Journal of Woman and Child Health Research
