中医虚证的抗氧化指标与红细胞免疫功能变化的临床观察

Clinical Observation on Relationship of Antioxidation Criteria and Immune Function of Erythrocyte in Patients with Asthenia Syndrome

本研究对３１例老年气阴两虚证患者的抗氧化指标与红细胞免疫功能进行了观察。结果表明，与健康对照组比较，老年气阴两虚证患者红细胞超氧化物歧化酶（ＳＯＤ）活性明显降低（Ｐ＜０．０１），血清过氧化脂质（ＬＰＯ）含量明显增高（Ｐ＜０．０１），红细胞Ｃ３ｂ受体花环率（ＲＣ３ｂＲＲ）明显降低（Ｐ＜０．０１），红细胞免疫复合物花环率（ＲＩＣＲ）明显升高（Ｐ＜０．０１）。气阴两虚证红细胞ＳＯＤ活性与ＲＣ３ｂＲＲ呈正相关（ｒ＝０．３８１，Ｐ＜０．０５），血清ＬＰＯ与ＲＣ３ｂＲＲ呈负相关（ｒ＝－０．３９５．Ｐ＜０．０５）。

Results of observation on 31 patients of Qi-Yin Deficiency Syndrome showed that as compared with normal person, the superoxide dismutase (SOD) activity of erythrocyte in patients was lowered,the content of serum lipid peroxide (LPO) increased, the rosette rate of red cell C3b receptor (RC3bRR) lowered but that of red cell immune complex was elevated significantly (P < 0. 01). There were a positive correlation between erythrocyte SOD activity and RC3bRR (r=0.381,P<0. 05),and a negative correlation between serum LPO level and RC3bRR (r=-0.395,P<0. 05).