复方皂矾丸在放射治疗中的临床疗效观察

Clinical Observation of Compound Zaofan Pills in Radiotherapy

目的:观察复方皂矾丸加放疗治疗恶性肿瘤改善生存质量、升高白细胞作用与不良反应。方法:采用随机对照方法将120例患者分为复方皂矾丸加放疗的治疗组55例,单纯放疗的对照组65例。结果:治疗组升白有效率为74.5%,对照组为13.8%,两组有显著性差异(P<0.01)。两组患者治疗前后症状改善,卡氏评分和体重变化均有显著差异(P<0.05)。结论:复方皂矾丸可明显升高白细胞并改善生存质量,且不良反应小。

Objective： To study the effects of Compound Zaofan Pills （CZP） on improveing the life quality, increasing the number of white blood cell and toxic responses of CZP. Methods. Divide cases into two groups at random. CZP combined radiotherapy group （treatment group） was 55 cases. Radiotherapy alone group （control group） was 65 cases. Results： （ 1 ） The effective rate to ascend the number of white blood cell of treatment group was 74.5 %, whereas the effective rate of control group was 13.8 %. There was a significant difference between the two groups （P 〈 0.01）. （2） After the treatment, the symptoms ameliorate, KPS score and body weight had significant difference between the two groups （ P 〈 0.05）. （3） There was not significant difference in responses of gastrointestinal tract between the two groups （ P 〉 0.05）. Conclusion： CZP can greatly increase the number of white blood cell and improve the life qualities while relesing the toxic responses.