超声辐射合成1-甲氧基-4-(2-乙基)己氧基苯

Supersonic synthesis of 1-methoxy-4-(2-ethyl) hexyloxybeneze

以对甲氧基苯酚和CH2BrCH（CH2CH3）（CH2）3CH3为原料，乙醇钠和乙醇为溶剂，在血气保护下，用超声辐射催化合成1-甲氧基-4-（2-乙基）己氧基苯，反应5—6h，收率可达86％-88．5％。反应的适宜条件为：MOPh和CH2BrCH（CH2CH3）（C02）3CH3物质的量比为1：1．5，乙醇钠的浓度2．5mol／L（溶剂CH3CH2OH），超声频率40kHz。

1-Methoxy-4-（ 2-ethyl ） hexyloxybeneze （ MOEHOB ） was synthesized by the reaction of p-methoxy phenol （MOPh） with CH2 BrCH（ CH2CH3 ） （ CH2 ）3CH3 in argon atmosphere under supersonic irradiation in the solution of sodium ethoxide in ethanol, the yields were 86% -88.5%, The optimum reaction conditions： molar ratio of MOPh/CH2BrCH（CH2CH3） （CH2）3- CH3 was 1 ： 1.5, the concentratim of sodium ethanolxyide was 2.5 mol/L, the frequency of the supersound was 40kHz, the reaction time was 5 - 6h.