牛初乳脂质营养液用于严重烫伤大鼠的研究

Treatment of Severely Scalding injured Rats with Bovine Colostric Lipid

目的：探索牛初乳脂质营养液用作烫伤病人营养增补剂的可能性。方法：分析了烫伤大鼠服用牛初乳脂质营养液第９天和２５天时血浆中脂溶性维生素、β－胡萝卜素、ＳＯＤ和ＬＰＯ的水平，作了烫伤动物的常规观察和存活率测定。结果：服用营养液能显著升高与生物体内抗氧化作用有关的脂溶性维生素，β－胡萝卜素和ＳＯＤ的水平，降低对生物体有害的ＬＰＯ的含量，明显提高烫伤动物的存活率。结论：该营养液可用作烫伤病人综合治疗的营养增补剂。

Aim: To explore the capability of using bovine colostric lipid as the nourishment for patients with scald. Methods: The levels of fat soluble vitamins, superoxide dismutase (SOD) and lipid peroxides (LPO) in rat plasma were measured at the day 9 and 25 after severely scalded injury and treated with nutrimental fluid or vehicle. The routine examination and the number of survivor were daily observed. Results: The contents of fat soluble vitamins, β carotene and SOD that were all able to promote antioxidant action in body were markedly increased. The level of LPO that would induce harmful injury to body was markedly decreased. The survival rate of scalded rats which were treated with nutrimental fluid was significantly enhanced when compared with vehicle control. Conclusion: This fluid may be very suitable for patient subjected to scald or burn.