牦牛部分功能基因密码子偏好性的聚类分析

Cluster Analysis on the Codon Usage Bias of Different Genes in Yak

本文利用系统聚类法对牦牛部分功能基因进行了密码子偏好性的聚类分析,并同普通牛和猪的相关基因作了对比。结果表明:不同物种间,类型或功能相似的基因具有相近的密码子偏好性;三个物种的基因在类型或功能上的差异决定了其密码子使用偏好性的聚类结果;在功能或类型相近的前提下,物种间的差异在一定程度上决定了密码子使用的偏好性。

The relative synonymous codon usage frequency of different genes from three domestic animals （Bos grunniens,Bos taurus,Sus scrof） was analyzed by a hierarchical cluster method. The result suggested that gene function was the dominant factor that determined codon usage bias, while species was a minor factor that determined further difference in codon usage bias for genes with similar functions.