ICP-MS法测定4种中药材中重金属含量

Determination of heavy metals in four traditional Chinese medicines by ICP-MS

目的：建立电感耦合等离子体质谱（ICP-Ms）法测定4种中药材中砷、汞、铅、镉含量的方法。方法：样品经微波消解，以In作为内标，补偿基体效应，采用ICP-MS同时测定上述4种元素。结果：对于所测元素，校准曲线的相关系数r〉0．9992，回收率为97．5％-108．0％，RSD〈11．6％。结论：本研究所建立的方法具有简便、快速、准确、灵敏度高的优点，可用于质量控制，并为不同产地不同种类的中药材中重金属含量测定提供了方法。

Objective： To establish a ICP-MS method for the determination of heavy metals, including As, Hg, Pb, CA, in four traditional Chinese medicines, Method： The samples were digested by elosed-versel microwave. The four heavy metals were directly analyzed by ICP-MS. Seleet internal standard element In for the method by which the analyse signal drife is corrected by the signal of another element （internal standard elements） added Io both the standard solution and sample.Result： For all of the analyzed heary methals, the correlative coefficient of the calibration curves was over 0.999 2. The recovery rates of the procedure were 97.5%-108.0%, and its RSD was lower than 11.6%. Conclution： This method was convenient, quick-acquired, accurate and highly sensitive. The method can be used for the quality control of trace elements in traditional Chinese medicines and for the contents determination of traditional Chinese medicines from different habitats and species.