摘要
瞄准：评估为肝细胞癌(HCC ) 的早察觉屏蔽的 ultrasonographic 的有效性。方法：为长期的肝疾病有 ultrasonography (美国) 的 14968 个病人的数据从 1995 年 6 月被收集进一个数据库节目到 2005 年 6 月。为 HCC 的风险因素也被学习。重复了美国的 6089 个病人的一个总数被注册， 264 个病人在后续期间与 HCC 被诊断(平均数， 39 瞬间) 。结果：小 HCC 的察觉率(【= 在直径的 3 厘米) 是 67.7% 。在 6 瞬间的间隔屏蔽检测的肿瘤尺寸在更长的间隔是比那显著地小的。仅仅， 29.3% HCC 病人有一座提高的浆液高山哈在 400 ng/mL 上面的 fetoprotein (法新社) 水平。HCC 开发的风险比在有长期的肝炎(4.2%) 的病人在有肝肝硬化(10.9%) 和丙肝(9.0%) 的病人在后续期间是更高的，肝炎 B (4.9%) 和 non-B， non-C 肝炎(NBNC， 3.9%) 。结论：在 6 瞬间的间隔屏蔽的美国对超过 40 岁的高风险的病人有益， HCC 的早察觉延长幸存。
AIM： To evaluate the effectiveness of ultrasonographic screening for early detection of hepatocellular carcinoma （HCC）.
METHODS： The data of 14 968 patients who had ultrasonography （US） for chronic liver diseases were collected into a database program from June 1995 to June 2005. The risk factors for HCC were also studied. A total of 6089 patients who had repeated US were enrolled, 264 patients were diagnosed with HCC during follow-up （mean, 39 mo）.
RESULTS： The detection rate of small HCC （≤ 3 cm in diameter） was 67.7%. The tumor size detected by screening at the intervals of 6 mo was significantly smaller than that at longer intervals. Only 29.3% of HCC patients had an elevated serum alpha fetoprotein （AFP） level above 400 ng/mL. The risk of HCC development during follow-up was higher in patients with liver cirrhosis （10.9%） and hepatitis C （9.0%） than in patients with chronic hepatitis （4.2%）, hepatitis B （4.9%） and non-B, non-C hepatitis （NBNC, 3.9%）. CONCLUSION： US screening at a interval of 6 mo is beneficial to high-risk patients over 40 years old and the early detection of HCC prolongs survival.
