腹水超滤浓缩-细菌过滤回输腹腔治疗肝炎肝硬化合并自发性细菌性腹膜炎的临床疗效分析

Abdominal reinfusion of concentrated ascites after ultrafiltration and bacterium filtration for patients with post-hepatitis cirrhosis complicating spontaneous bacteria peritonitis

目的评估腹水超滤浓缩细菌过滤回输腹腔技术治疗肝炎肝硬化合并自发性细菌性腹膜炎患者的临床疗效。方法110例肝炎肝硬化合并自发性细菌性腹膜炎患者随机分为研究组和对照组,两组患者均采用保肝、利尿、对症、支持及静脉滴注抗生素等常规治疗,疗程2周。研究组在常规治疗基础上,采用腹水超滤浓缩细菌过滤回输腹腔治疗;对照组在常规治疗基础上,采用腹腔穿刺放液治疗。结果治疗后研究组腹水蛋白及补体C3水平明显高于对照组(P<0.01),研究组血清白蛋白水平明显高于对照组(P<0.01),研究组临床疗效明显好于对照组(P<0.01)。结论腹水超滤浓缩细菌过滤回输腹腔技术治疗肝炎肝硬化合并自发性细菌性腹膜炎患者的临床疗效明显好于腹腔穿刺放液治疗。

Objective To evaluate clinical efficacy of reinfusion of concentrated ascites after uhrafihration and bacterium filtration into abdominal cavity for posthepatitis cirrhosis complicating spontaneous bacterial peritonitis. Methods One hundred and ten patients with posthepatitis cirrhosis complicating spontaneous bacterial peritonitis were randomly divided into study group and control group. Patients in both groups received conventional therapy for 2 weeks. At the same time patients in study group received the concentrated ascites after uhrafiltration and bacterium filtration reinfused into abdominal cavity while patients in control group only received abdominal paracentesis apocenosis concomitently for 2 weeks. Results After 2 weeks of treatment, complement C3 and serum albumin levels in study group were higher than in control group（ P 〈 0.01 ）, clinical efficacy in study group was better than in control group（ P 〈 0.01 ）. Conclusion Clinical efficacy of the ascites uhrafihration concentration and bacterium filtration back-infusion abdominal cavity treatment for posthepatitic cirrhosis complicating spontaneous bacterial peritonitis was better than abdominal paracentesis apocenosis.