甲硝唑液创面注射预防阑尾切口感染临床观察

Clinical Study on Metronidazole Injection in Preventing Incisiona Infection in Appendectomy

目的:探讨甲硝唑液创面注射预防阑尾切口感染的疗效。方法:100例急性化脓性阑尾炎手术病例,随机分为治疗组和对照组各50例。治疗组用甲硝唑液行创面注射,对照组按常规处理,观察两组患者手术后切口的感染率。结果:治疗组感染率8%,对照组感染率为18%,两者比较有统计学意义(P<0.05)。结论:甲硝唑液创面注射预防阑尾切口感染简便、经济、安全、有效。

Objective：To investigate the efficacy of metronidazole injection in preventing incision infection in appendectomy. Methods： One hundred patients with acute pyogenic appendicitis were divided into two groups. Incisions were injected with metronidazole in the study group, while the control group was treated in the same way as the study group except metronidazole injection. Results： The rate of incision infection in the study group was 8%, and 18% in the control group. There was significant difference in the rate of incision infection between the two groups （ P 〈0.05）. Conclusion： Metronidazole injection is convenient, economical, safe and effective to prevent incision infection in appendectomy.