高压氧治疗急性脑梗塞的临床分析

A clinical analysis of hyperbaric oxygen therapy in treating patients with acute cerebral infarction

目的观察高压氧(HBO)治疗急性脑梗塞患者的疗效并进行临床分析。方法回顾性研究我院2000年1月至2005年2月急性脑梗塞住院病例共466例。其中高压氧＋药物治疗组(HBO组)303例；单纯药物治疗组(对照组)163例。根据“欧洲卒中量表”(ESS)对HBO组于HBO治疗前、后,对照组于人、出院时分别进行评分并观察疗效。结果HBO组治疗重、中度脑梗塞患者与对照组相比,ESS评分分别有非常显著性差异(P＜0．01)、显著性差异(P＜0．05)；HBO组治疗椎-基底动脉系统脑梗塞与对照组相比,差异有显著性意义(P＜0．05)。HBO治疗次数超过10次组与对照组相比,ESS评分有显著性差异(P＜0．05)。结论重、中度急性脑梗塞和椎-基底动脉系统脑梗塞HBO综合治疗好于单纯药物治疗。HBO治疗次数超过10次组的疗效优于HBO治疗次数不足10次组。

Objective To investigate the effect of hyperbaric oxygen therapy （HBOT） on patients with acute cerebral infarction （ACI）. Methods In this retrospective study, 466 patients suffered from ACI and hospitalized from Jan. 2000 to Feb. 2005 were divided into HBOT plus drug therapy group （HBO group, 303 eases） and drug therapy group （control group, 163 cases）. ＂The European Stroke Scale＂ （ESS） was used to evaluate patients in the HBO group before and after HBOT and to evaluate patients in the control group at admission and discharge, and the two groups were compared. Results As to severe and moderate ACI, the HBO group was significantly different from the control group in ESS scores （ P 〈 0.01 or 0.05 ） ; as to vertebraarteria basilaris ACI, the HBO group was significantly different from the control group in ESS scores（P 〈 0. 05） ; the HBO group was significantly different from the control group when the treatment time was over 10 times （P 〈 0.05）. Conclusions Compared with drug therapy, HBOT had better effect on severe, moderate ACI and vertebra-arteria basilaria, and HBOT had a better effect when the treatment time was over 10 times.