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动物受精过程中卵子Ca^(2+)释放机制 被引量：1

Ca^(2+) RELEASE MECHANISMS OF OOCYTE AT FERTILIZATION
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摘要 Ca2+是动物受精过程中卵内重要的第二信使,它对于皮质颗粒的排放、减数分裂的恢复、原核形成等过程具有重要的作用,受精过程中Ca2+的释放机制研究是当今受精生物学研究的热点之一,已有的研究结果表明动物卵子在受精过程中有三种Ca2+释放机制:由1,4,5,三磷酸肌醇引发内质网中储存的Ca2+释放、由环腺苷酸二核苷酸磷核糖引发与其相关联的钙库Ca2+释放和烟酸腺嘌呤二核苷酸磷酸引发的与其相关联的钙库Ca2+释放. Eggs from different animal species were studied to date elicit single or repetitive Ca^2＋ transients in response to fertilizing sperm. As an important second messenger, Ca^2＋ triggers a broad range of cellular reactions, including cortical granule release, completion of meiosis and pronuclear formation in oocyte. There are three mechanisms for Ca^2＋ release： inositol 1,4, 5 - trisphosphate pathway, cyclic ADP - fibose pathway and nicotinic acid adenine dinucleotide phosphate pathway.
作者 郑克刚 孟小倩 李云龙
机构地区 山东师范大学生命科学学院动物抗性省重点实验室
出处 《山东师范大学学报（自然科学版）》 CAS 2006年第3期120-122,共3页 Journal of Shandong Normal University(Natural Science)
关键词 受精 CA^2+ IP3 CADPR NAADP fertilization Ca^2＋ IP3 cADPR NAADP
分类号 Q492.5 [生物学—生理学]
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参考文献19

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同被引文献19

  • 1焦园园,杨桂文,安利国,叶棋浓.CCN蛋白家族研究进展[J].山东师范大学学报（自然科学版）,2005,20(3):77-79. 被引量：6
  • 2Coleman Lindsley R, Jennifer G Gill, Michael Kyba et al. Canonical Wnt signaling is required for development of embryonic stem cell - derived mesoderm Development[J]. 2006, (133): 3 787- 3 796.
  • 3Zhongling Feng, Ewa Carrier. A role of Wnt signalling pathway in the hematopoietic differentiation of murine embryonic stem cells[J]. Nature, 2003, (423) :409 - 414.
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  • 5Peggy Kirstetter, Kristina Anderson, Bo T Porse, et al. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block[J]. Nat Immunol, 2006, (7) : 1 048 - 1 056.
  • 6Scheller M, Huelsken J, Rosenbauer F, Taketo M M, et al. Hematopoietic stem coil and multilineage defects generated by constitutive β- Catenin activation[J].Nat Immunol, 2006, (10):1 037-1 047.
  • 7Gordon Keller Embryonic stem cell differentiation: emergence of a new era in biology and medicine Genes & Dev, 2005, (19) : 1 129 - 1 155.
  • 8Haegele L, Ingold B, Naumann H, et al. Wnt signalling inhibits neural differentiation of embryonic stem cells by controlling bone morphogentic protein expression[J]. Molecular and Celluar Neuroscience, 2003, 696- 708.
  • 9Maurice Kleber, Hye - Youn Lee, Heiko Wuntak, et al. Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling[J]. J. Cell Biol, 2005, (169): 309-320.
  • 10Hye-Youn Lee, Maurice Kleber, Lisette Hari, et al. Instructive Role of Wnt/β- Catenin in Sensory Fate Specification in Neural Crest Stem Cells[J] Seien, 2004, (5660): 1 020- 1 023.

引证文献1

山东师范大学学报（自然科学版）
2006年 第3期

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