期刊文献+

内关穴不同治法对心肌缺血再灌注大鼠心电图及心肌形态学的影响 被引量:7

Effect of Different Therapy in Neiguan Acupoint on Morphologic and ECG in Myocardial Ischemia Perfusion Lesion Rats
下载PDF
导出
摘要 目的通过内关穴电针、注射复方丹参注射液及注射注射用水对心肌缺血再灌注大鼠心电图及心肌形态学的影响,探讨不同治法的治疗效应。方法将60只Wistar大鼠随机分为假手术组,模型组,内关电针组,内关注药组、内关注水组、合谷电针组。采用大鼠冠状动脉左前降支根部穿线结扎建立心肌缺血再灌注损伤模型。应用心电图和光学显微镜分别观察STⅡ的改变及心肌病理形态变化。结果结扎后20、40min及松扎后60min,各组STⅡ差值较假手术组均有不同程度的升高,依次为模型组、合谷电针组、内关注水组、内关电针组、内关注药组(P<0.05或P<0.01)。结论内关注药组、内关电针组和内关注水组均能不同程度降低实验性心肌缺血大鼠的STⅡ,改善心肌缺血程度,其效果为内关注药组>内关电针组>内关注水组。合谷电针组对降低STⅡ及受损心肌的改善无明显影响。 Objective To investigate the electro-acupuncturing, injecting compounded water in Neiguan therapeutic effect of different methods with Radix Salviae Miltiorrhizae injection and injecting Methods 60 rats were divided into fake operation, model, electr-acupuncturing in Neiguan, medicine injecting in Neiguan, water injecting in Neiguan and electro-acupuncturing in Hegu groups. The myocardial ischemia reperfusion lesion model was induced by ligating left anterior descending branch root of the coronary artery. And the changes of STⅡ in ECG and myocardial morphologic were observed with ECG and microscope. Results Compared with the fake operation group 20 min and 40 min after ligating and 60 min after untied ligating, the D-values of STⅡ in all other groups were increased (P〈0.05 or P〈0.01) in different degree, in order of following: model, electro-acupuncturing in Hegu, injecting water in Neiguan, electro-acupuncturing in Neiguan and injecting medicine in Neiguan groups. Conclusion The STⅡ in experimental myocardial ischemia can be decreased and the level of myocardial ischemia be improved with injecting medicine, electro-acupuncturing and injecting water in Neiguan, in which the effect is in orders of injecting medicine, electro-acupuncturing and injecting water. But electro-acupuncturing in Hegu is not effective to decrease STⅡ and improve the injured myocardium.
出处 《湖南中医学院学报》 CAS 2006年第4期48-50,共3页 Journal of Hunan College of Traditional Chinese Medicine
基金 湖南省科技厅重点资助项目(02SSY2005)
关键词 内关 合谷 电针 穴位注射 缺血再灌注损伤 心电图 组织形态学 大鼠 Neiguan electro acupuncture acupoint-injecting ischemia reperfusion lesion ECG morphologic rats
  • 相关文献

参考文献6

二级参考文献43

  • 1潘宜智,吾柏铭,洪小苏,张莉丽,刘励军,陈建昌,高岚.血小板活化在不稳定性心绞痛中的意义[J].中华心血管病杂志,1994,22(4):247-248. 被引量:35
  • 2胡国恒,谭元生.补气化瘀豁痰通络法治疗冠心病心绞痛的临床及实验研究[J].中国中医急症,1995,4(4):156-158. 被引量:10
  • 3司福中,欧阳明刚,盛春永,陈玉萍,李勇,沈学谦.不同剂量阿司匹林对冠心病患者血小板活性和数目的影响[J].中华内科杂志,1996,35(8):524-526. 被引量:23
  • 4陈树林,李育良.内关、心俞与心脏相关的神经基础[J].中国针灸,1996,16(12):33-35. 被引量:41
  • 5吴国新 李福刚 李佩霞 等.血小板颗粒膜蛋白(GMP-140)的放射免疫学测定[J].中华血液学杂志,1992,13:99-99.
  • 6[1]Murry CE,Jennings RB,Reimer KA.Preconditioning with ischemia:A delay of lethal cell injury in ischemic myocardium[J].Circulation,1986,74(5):1124-1136.
  • 7[2]Yang XM,Baxter GF,Heads RJ,et al.Infarct limitation of the second window of protection in a conscious rabbit model[J].Cardiovasc Res,1996,31(5):777-783.
  • 8[3]Stambaugh K,Elliott GT,Jacobson KA,et al.Additive effects of late preconditioning produced by monophosphoryl lipid A and the early preconditioning mediated by adenosine receptors and KATP channel[J].Circulation.1999,99(25):3300-3307.
  • 9[4]Lascano EC,Negroni JA,del Valle HF,et al.Left ventricular regional systolic and diastolic function in conscious sheep undergoing ischemic preconditioning[J].Cardiovasc Res,1999,41(1):77-86.
  • 10[5]Vegh A,Papp JG,Parratt JR.Prevention by dexamethasone of the marked antiarrythmic effects of preconditioning induced 20h after rapid cardiac pacing[J].Br J Phaemacol,1994,113:1081.

共引文献109

同被引文献121

引证文献7

二级引证文献48

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部