老年人脑卒中患者急性期并发抑郁的研究

Study on thc Depression in Elderly Patients with Acute Stroke.

目的探讨老年人卒中后急性期抑郁状态（PSD）的发生率及预后。方法对58例老年人卒中患者急性期用汉密尔顿（HAMD）抑郁量表进行测试，对符合老年人PSD诊断的23例患者给予5．羟色胺再摄取抑制荆（SSRI）类药物治疗，分别于卒中后第2、3、4周进行评定，用HAMD减分率判断疗效。结果老年人脑卒中患者急性期PSD的发生率为37．9％，轻、中度抑郁发生率33．3％，用SSRI类药物治疗1个月，治愈14例，好转8例，无效1例。结论老年人卒中后急性期PSD发生率高于一般人群：SSRI类药物应用于PSD疗效显著。在治疗脑卒中的同时应积极治疗抑郁状态。

Objective To investigate the occurrence rate and prognosis of post stroke depression （PSD） in elderly patients with acute stroke. Methods 58 hamilton depression rating scales （HAMD）.In the 58 cases of PSD, 23 cases that had depression were treated with selective serotonin-reupdate in hibitors （SSRI）; then test the patients 2, 3, 4 weeks after stroke. HAMD reducing scores rate was used to evaluate the curative effect of SSRI treatment for occurrence rate of PSD was 37.9%;33.3% patients were shown to have mild and moderate depression .A total of 23 cases were treated with SSRI for one month ,and there were 14 cured, 8 better and 1 ineffective results. Conclusion The occurrence rate of PSD in elderly patients with acute stroke was higher than a general crowd： the therapeutic effect of SSRI treatment for PSD was obvious. Depression should be positively treated in the course of stroke treatment.