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非瓣膜病性房颤患者血清VCAM-1水平及电复律的影响 被引量:1

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摘要 目的研究非瓣膜病性房颤患者的血清血管细胞黏附分子-1(vascu lar cell adhesion molecu le-1,VCAM-1)水平及电复律对其影响。方法选择2005年1月至2005年5月于我院心内科住院的非瓣膜病性房颤患者30人及19例年龄、性别相匹配的健康人,应用酶联免疫法测定血清VCAM-1水平,房颤组内电复律成功的20人在1个月后复查血清VCAM-1水平。结果房颤组患者血清VCAM-1水平明显高于对照组〔(727.8±71.7)vs(169.7±82.0)ng/m l,P<0.01〕,电复律后1个月仍为窦性心律者其血清VCAM-1降至正常水平(698.1±72.7 vs 195.6±65.1 ng/m l,P<0.01)。结论非瓣膜病性房颤患者存在内皮功能紊乱,恢复窦性心律1个月内内皮功能恢复;VCAM-1对房颤的发生发展起一定作用。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2006年第2期152-153,共2页 Chinese Journal of Gerontology
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