期刊文献+

豫东地区46例弱智患儿细胞遗传学分析与危险因素调查

下载PDF
导出
摘要 目的:调查豫东地区弱智患儿的发病情况及危险因素。方法:以豫东地区为主,对来该附院遗传咨询的弱智患儿及父母作为调查对象,采取染色体分析和抽样调查的方法。结果:经调查分析了解到46例弱智患儿90%的来自城市流动人口和农村人群中,其中染色体异常综合征29例,占63.04%,并且男患者多于女患者(19∶10)。其发病因素与父母的文化程度、优生知识知晓度、受旧传统思想影响度等因素有关。结论:弱智患儿发病的危险因素与多因素有关。
出处 《中国妇幼保健》 CAS 北大核心 2006年第16期2274-2275,共2页 Maternal and Child Health Care of China
  • 相关文献

参考文献5

二级参考文献23

  • 1石国光.广州市儿童医院门诊VitD缺乏性佝偻病发展现状调研[J].中国妇幼保健,2003,18(4):50-52. 被引量:4
  • 2何晓芸,余静,吴晓季,刘亚群,王安民,谢坚,刘蓉,赵小玲.绵阳市城区0~6岁儿童佝偻病调查及相关因素分析[J].中国妇幼保健,2003,18(4):53-54. 被引量:22
  • 3Gardo S, Bajnoczky K. Cytogenetic analysis of spontaneous abortions with direct analysis of chorionic villi. Eur J Obstet Gynecol ReprodBiol, 1992, 47 (2): 117-120.
  • 4Hobbs CA, Cleves MA, Lauer RM, et al. Preferential transmission of the MTHFR 677T allele to infants with Down syndrome: implications for a survival advantage. Am J Med Genet, 2002, 113: 9-14.
  • 5Bosco P, Gueant-Rodriguez RM, Anello G, et al. Methionine synthase ( MTR ) 2756 ( A → G ) polymorphism, double heterozygosity methionine synthase 2756 AG/methionine synthase reductase(MTRR) 66 AG, and elevated homocysteinemia are three risk factors for having a child with Down syndrome. Am J Med Genet A. 2003, 121 (3): 219-224.
  • 6Yao YG, Duh EJ. VEGF selectively induces Down syndrome critical region 1 gene expression in endothelial cells: amechanism for feedback regulation of angiogenesis? Biochem Biophys Res Commun, 2004, 321 (3): 648-656.
  • 7Pekka T,Vilho H,Riitta S,et al. Increased Nuchal Translucency as a Marker for Fetal Chromosomal Defects. N Engl J Med,1997, 337: 1654-1658.
  • 8Jauniaux E, Brown R, Snijders RJ, et al. Early prenatal diagnosis of triploidy. Am J Obstet Gynecol, 1997, 176 (3): 550-554.
  • 9Jauniaux E, Gavrill P, Khun P, et al. Fetal heart rate and umbilico-placental Doppler flow velocity waveforms in early pregnancies with a chromosomal abnormality and/or an increased nuchal translucency thickness. Hum Reprod, 1996,11 (2):435-439.
  • 10Awwad JT, Azar GB, Karam KS, et al. Ear length: a potential sonographic marker for Down syndrome. Int J Gynaecol Obstet,1994, 44 (3):233-238.

共引文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部